Epor macrophage wei li
Webonstrated that EPOR is expressed in nonerythroid cells, such as the brain, kidneys, heart, and various tumor cell lines [20– 24]. Specifically, it has been reported that EPOR can … WebThe identity of EBI macrophages has thus far remained elusive. Given that Epo is essential for erythropoiesis and that Epor is expressed in numerous nonerythroid cells, we hypothesized that EBI macrophages express Epor so that Epo can act on both erythroid cells and EBI macrophages simultaneously to ensure efficient erythropoiesis.
Epor macrophage wei li
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WebNov 18, 2024 · The erythropoietin receptor (EpoR) has traditionally been thought of as an erythroid-specific gene. Notably, accumulating evidence suggests that EpoR is expressed well beyond erythroid cells. However, the expression of EpoR in non-erythroid cells has been controversial. WebActivated erythropoietin (EPO) receptor (EPOR) signaling causes erythrocytosis. The important role of macrophages for the erythroid expansion and differentiation process has been reported, both in baseline and stress erythropoiesis. However, the significance of EPOR signaling for regulation of macrophages contributing to erythropoiesis has not …
WebAug 1, 2024 · Cytospin image of an erythroblastic island formed between an EPO-pretreated macrophage (the cell in the center) and erythroblasts (surrounding cells). EPO/EPOR–mediated signal transduction in human EPOR + macrophages enhances erythroblastic island formation. See the article by Li et al on page 480. WebFeb 1, 2024 · In our previous investigations, we found that levels of EPO and EPOR increased during zymosan A-induced peritonitis, EPOR only expressed in macrophages …
WebNov 18, 2024 · Notably, accumulating evidence suggests that EpoR is expressed well beyond erythroid cells. However, the expression of EpoR in non-erythroid cells has been … WebNational Center for Biotechnology Information
WebBackground: Tissue-resident macrophages can be educated to tumor-associated macrophages (TAMs) by the tumor microenvironment and many types of macrophages …
WebAug 1, 2024 · We show that in bone marrow (BM) and fetal liver, a subset of macrophages express Epor-eGFP. Imaging flow cytometry analyses revealed that >90% of native EBIs … sticky floor tiles amazonWebTAMs expressing EPOR and CD163+EPOR+ macrophages as TAMs in osteosarcoma lung metastasis patients, which are highly associated with tumor aggressiveness are characterized. Background Tissue-resident macrophages can be educated to tumor-associated macrophages (TAMs) by the tumor microenvironment and many types of … sticky fly trapsWebAug 1, 2024 · Erythroblastic island (EBI), composed of a central macrophage surrounded by developing erythroid cells, is a structure found in hematopoietic tissues such as fetal liver and bone marrow. It is the first described hematopoietic … sticky fly tape paper ribbonWebNov 1, 2024 · EpoR-tdTomato-Cre mice enable identification of EpoR expression in subsets of tissue macrophages and hematopoietic cells. ... sticky fly traps tescoWebNov 29, 2024 · It has been reported that the Epo receptor (Epor) is expressed in peritoneal macrophages. These findings promoted us to speculate that EBI central macrophages may express Epor so that Epo... sticky flooring planksWebNov 18, 2024 · Functional EpoR is expressed in subsets of tissue macrophages and hematopoietic cells. EpoR-tdTomato-Cre mouse line provides a powerful tool for identification of EpoR expression and gene manipulation in EpoR-expressing cells. Sign In - EpoR-tdTomato-Cre mice enable identification of EpoR expression in ... sticky fly traps raidWebDec 1, 2024 · Wen Zhang 1 , Yao Wang 1 , Chuanwei Li 2 , Yu Xu 1 , Xia Wang 1 , Di Wu 1 , Zhan Gao 1 , Hang Qian 1 ... Moreover, EPO treatment hardly promotes M2 polarization in Rab26 knockout (KO) macrophages through EPOR. Collectively, macrophage EPOR signaling is impaired by eCIRP through Rab26 during ALI/ARDS, leading to the … sticky fly paper trap