Cytohesin-1
WebImmunofluorescent analysis of Cytohesin 1, 2 in HeLa Cells. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with a Cytohesin 1, 2 monoclonal antibody (Product # MA1-062) at a dilution of 1:100 overnight at 4 C, washed with PBS and incubated with a DyLight-488 conjugated ... WebJul 7, 1998 · Cytohesin-1 (B2–1) is a guanine nucleotide exchange factor for human ADP ribosylation factor (Arf) GTPases, which are important for vesicular protein trafficking and coatamer assembly in the cell. Cytohesin-1 also has been reported to promote cellular adhesion via binding to the β2 integrin cytoplasmic domain.
Cytohesin-1
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WebThis gene encodes a member of the cytohesin (CYTH) family, formerly known as the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. Cytohesin family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. WebTDR Targets ID: 578688 Echinococcus granulosus, cytohesin 1 Source Database / ID: GeneDB pI: 8.4469 Length (AA): 449 MW (Da): 50086 Paralog Number: 0
WebJun 6, 2000 · Cytohesin-1 comprises an N-terminal coiled-coil domain, which may aid in oligomerization, a central Sec7 domain and a C-terminal module including the pleckstrin … WebAug 18, 2003 · Cytoplasmic exchange factors for ARFs have been identified; they are called cytohesin-1 , ARNO (cytohesin-2) and GRP-1 (cytohesin-3) . Cytohesin-1 is a 47-kDa cytoplasmic protein which comprises a coiled-coil N-terminus, a central Sec7 domain and a C-terminal portion containing a pleckstrin homology domain and a polybasic sequence, …
WebApr 14, 2015 · The cytohesins are a class of BFA-resistant small GEFs for ADP-ribosylation factors (ARFs), which regulate cytoskeletal organization, integrin activation, or integrin signaling. The application of SecinH3 in human liver cells showed that insulin receptor complex-associated cytohesins are required for insulin signaling. WebFeb 23, 2024 · Abstract. Adhesion is a key component of hematopoietic stem cell regulation mediating homing and retention to the niche in the bone marrow. Here, using an RNA interference screen, we identify cytohesin 1 (CYTH1) as a critical mediator of adhesive properties in primary human cord blood–derived hematopoietic stem and progenitor …
WebAug 18, 2003 · Cytoplasmic exchange factors for ARFs have been identified; they are called cytohesin-1 , ARNO (cytohesin-2) and GRP-1 (cytohesin-3) . Cytohesin-1 is a 47 …
Webfindings suggest that cytohesin-1 is a key regulator of neutrophil adhesion to endothelial cells and to components of extracellular matrix, which may influence cell emigration … open bash file ubuntuWebThe cytohesin-1–targeting vector was constructed by replacing the ~3.6-kb Xba I fragment containing exons 4 to 7 of cytohesin-1 within the fragment containing exons 4 to 11, … iowa is in what conferenceWebFeb 23, 2024 · Initially, CYTH1 was identified in a protein-protein interaction screen and found to interact specifically with the cytoplasmic part of the integrin β2 chain of LFA-1 … iowa is in what time zoneWebMay 3, 2024 · The cytohesin proteins, consisting of four closely related members (cytohesins-1, -2, -3, and -4), are a subfamily of the Sec7 domain-containing guanine nucleotide exchange factors for ADP... open bash history in vimWeb英文名称：Human Cytohesin Interacting Protein, CYTIP GENLISA™ ELISA . Krishgen: KBH2280: ... 中文名称：人类白细胞衍生趋化因子 1，LECT1 GENLISA™ ELISA试剂盒 . 英文名称：Human Leukocyte Cell Derived Chemotaxin 1, LECT1 GENLISA™ ELISA . Krishgen: KBH2292: open bash in powershellWebKolanus W, et al. alphaLbeta2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1 a cytoplasmic regulatory molecule. Cell 86: 233-242, 1996. PubMed: 8706128 ... Jang SI, et al. Activator protein 1 activity is involved in the regulation of the cell type-specific expression from the proximal promoter of the human profilaggrin gene. J. Biol ... iowa is known as the what stateWebCytohesin-2 is enriched in the perisynapse on the postsynaptic membrane of dorsal horn neurons and forms a protein complex with mGluR5 in the spinal cord. Central nervous system-specific cytohesin-2 conditional knockout mice exhibited reduced mechanical allodynia in inflammatory and neuropathic pain models. iowa isn\\u0027t real